Normal TROSY
●Large proteins
–Fast relaxation = Broader line widths
–Decrease in spectral resolution
1H – 15N TROSY
–Relaxation contributions from:
●Dipole-dipole (DD)
●Chemical shift anisotropy (CSA)
–DD and CSA interfere either constructively or destructively
–TROSY selects signals where destructive interference has occurred
●Cancelled out
–Results in sharper signals and increased resolution
I hold MRC CASE studentship with AstraZeneca and in the Faculty of Life Sciences based at the Manchester Institute of Biotechnology. My Phd research project is concentrated on understanding the Ras:Sos system that is key to the creation of new anti-cancer therapies. I am interested in examining and characterising the molecular interactions of the Ras:Sos system by various biophysical methods and computer-assisted data analysis in addition to the expression and purification of these proteins.

Saturday, 13 September 2014
Monday, 25 August 2014
ICMRBS 2014
At the ICMRBS conference 2014 in the beautiful city of Dallas, USA.
Very excited to hear the latest development in solution-NMR and networking.
Future more comprehensive updates to follow ;-)
http://www.icmrbs2014.org/Program/Program
Best wishes
Very excited to hear the latest development in solution-NMR and networking.
Future more comprehensive updates to follow ;-)
http://www.icmrbs2014.org/Program/Program
Best wishes
Monday, 11 August 2014
Biochemical society travel grant
I am delighted to have received a generous travel student grant from the biochemical society to attend the ICMRBS conference in Dallas, Texas USA.
I've just received support from the @biochemsoc General Travel Grants Fund to attend a conference.
I've just received support from the @biochemsoc General Travel Grants Fund to attend a conference.
Tuesday, 15 July 2014
Biotechnology YES
YES WE CAN! :-)
Hi folks
The Biotechnology Young Entrepreneurs Scheme (Biotechnology YES) is an innovative competition developed to raise awareness of the commercialisation of bioscience ideas among early career researchers. I hope you have already submitted a team together and preparing to come up with an idea. I had a few friends who did it last year and previous to that. I heard nothing but great things about this competition and furthermore, I think it could be a great way to step outside of your comfort zone and try something entrepreneurial.
Here is a full timetable of what is to come
Hi folks
The Biotechnology Young Entrepreneurs Scheme (Biotechnology YES) is an innovative competition developed to raise awareness of the commercialisation of bioscience ideas among early career researchers. I hope you have already submitted a team together and preparing to come up with an idea. I had a few friends who did it last year and previous to that. I heard nothing but great things about this competition and furthermore, I think it could be a great way to step outside of your comfort zone and try something entrepreneurial.
Here is a full timetable of what is to come
Biotechnology YES 2014 Calendar
Application Deadline | 13 June | |
---|---|---|
Briefing Session | Nottingham | 13 August |
Plant, Microbial and Environmental Sciences Workshop | Hosted by Syngenta at Jealott's Hill | 8-10 October |
Chemistry YES Workshop | Manchester | 15-17 October |
North West Workshop | Manchester | 15-17 October |
BioMedical YES Workshop | Hosted by GSK and Stevenage Bioscience Catalyst | 22-24 October |
Food YES Workshop | Hosted by Leatherhead Food Research | 5-7 November |
Southern Workshop | Leatherhead | 5-7 November |
Scottish Workshop | Edinburgh | 12-14 November |
Final | London | 8 December |
Thursday, 10 July 2014
Enterprise School
Enterprise School, scheduled for Monday, 7th to Thursday, 10th July 2014 at The Low Wood Bay Hotel, Ambleside Road, Ambleside, LA23 1LP Cumbria.
Hi
I have just returned back from a very excellent enterprise business training school. The course has been designed based on teamwork in which each team will identify a commercial opportunity before refining their idea, looking at market research, intellectual property and raising finance as you would if you were starting a business or were working in industry. The sessions will be very interactive, and each group will have access to several different tutors for the entire course.
Employers frequently cite the need for “transferable skills” – those that allow you to become effective in your job and you will certainly be improving those skills during your time here. There will be ample opportunity to present information, pick up new skills, think creatively, absorb information quickly, network with others….. and work under pressure! It is also increasingly important to become an active learner, so a learning log you keep during your stay will help you to reflect on your achievements. This course was GREAT for learning about entrepreneurship!
https://mec.portals.mbs.ac.uk/Aboutus/Whygetinvolvedinenterprise.aspx
Hi
I have just returned back from a very excellent enterprise business training school. The course has been designed based on teamwork in which each team will identify a commercial opportunity before refining their idea, looking at market research, intellectual property and raising finance as you would if you were starting a business or were working in industry. The sessions will be very interactive, and each group will have access to several different tutors for the entire course.
Employers frequently cite the need for “transferable skills” – those that allow you to become effective in your job and you will certainly be improving those skills during your time here. There will be ample opportunity to present information, pick up new skills, think creatively, absorb information quickly, network with others….. and work under pressure! It is also increasingly important to become an active learner, so a learning log you keep during your stay will help you to reflect on your achievements. This course was GREAT for learning about entrepreneurship!
https://mec.portals.mbs.ac.uk/Aboutus/Whygetinvolvedinenterprise.aspx
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